Recombinant Human alpha-Parvin, His 是一種重組人 alpha-Parvin，在 C 末端有 His 標(biāo)簽。Alpha-parvin 是肌動(dòng)蛋白依賴(lài)過(guò)程的重要調(diào)節(jié)因子，如細(xì)胞擴(kuò)散和遷移。
Synonyms
rHualpha-Parvin, His; PARVA; MXRA2; alpha-Parvin ; 重組人α-Parvin，His
Species
HumanSource
E. coli Accession
Q9NVD7 Gene ID
55742 Molecular Weight
Approximately 58.0 kDa AA Sequence
MATSPQKSPS VPKSPTPKSP PSRKKDDSFL GKLGGTLARR KKAKEVSELQ EEGMNAINLP LSPIPFELDP EDTMLEENEV RTMVDPNSRS DPKLQELMKV LIDWINDVLV GERIIVKDLA EDLYDGQVLQ KLFEKLESEK LNVAEVTQSE IAQKQKLQTV LEKINETLKL PPRSIKWNVD SVHAKSLVAI LHLLVALSQY FRAPIRLPDH VSIQVVVVQK REGILQSRQI QEEITGNTEA LSGRHERDAF DTLFDHAPDK LNVVKKTLIT FVNKHLNKLN LEVTELETQF ADGVYLVLLM GLLEGYFVPL HSFFLTPDSF EQKVLNVSFA FELMQDGGLE KPKPRPEDIV NCDLKSTLRV LYNLFTKYRN VEHHHHHH Biological Activity
Data is not available. Appearance
Solution Formulation
Supplied as a 0.2 μm filter solution of 50 mM Tris, 150 mM NaCl, 40% Glycerol, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
N/A Storage & Stability
Recombinant Human alpha-Parvin, His (rHualpha-Parvin, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Shipping with dry ice. Background
Alpha-parvin (α-parvin; α-pv) is expressed ubiquitously and is an essential regulator of actin-dependent processes, such as cell spreading and migration. Alpha-parvin, a focal adhesion protein that couples integrins to actin cytoskeleton, is indispensable for epidermal morphogenesis and HF development. Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling[1][2] |
