Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed) 是在 C 末端帶有 His 標(biāo)簽的小鼠重組 Serpin A1a，由哺乳動(dòng)物表達(dá)系統(tǒng)產(chǎn)生，并表達(dá)編碼 Glu25-Lys413 的靶基因。
Synonyms
rMuAlpha-1-antitrypsin 1-1, His; Serpin A1a; Alpha-1-antitrypsin 1-1 ; 重組小鼠 Alpha-1-抗胰蛋白酶 1-1，His (HEK293 細(xì)胞表達(dá))
Species
MouseSource
HEK 293 Accession
P07758 Gene ID
20700 Molecular Weight
Approximately 52.0 kDa AA Sequence
EDVQETDTSQ KDQSPASHEI ATNLGDFAIS LYRELVHQSN TSNIFFSPVS IATAFAMLSL GSKGDTHTQI LEGLQFNLTQ TSEADIHKSF QHLLQTLNRP DSELQLSTGN GLFVNNDLKL VEKFLEEAKN HYQAEVFSVN FAESEEAKKV INDFVEKGTQ GKIAEAVKKL DQDTVFALAN YILFKGKWKK PFDPENTEEA EFHVDESTTV KVPMMTLSGM LHVHHCSTLS SWVLLMDYAG NATAVFLLPD DGKMQHLEQT LSKELISKFL LNRRRRLAQI HFPRLSISGE YNLKTLMSPL GITRIFNNGA DLSGITEENA PLKLSQAVHK AVLTIDETGT EAAAVTVLQM VPMSMPPILR FDHPFLFIIF EEHTQSPIFL GKVVDPTHKH HHHHH Biological Activity
Data is not available. Appearance
Solution Formulation
Supplied as a 0.2 μm filter solution of 20 mM Tris, 150 mM NaCl, pH 8.0. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
N/A Storage & Stability
Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed) (rMuAlpha-1-antitrypsin 1-1, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Shipping with dry ice. Background
Alpha-1-antitrypsin 1-1 (Serpin A1a; AAT) is the most abundant circulating serine protease inhibitor (serpin) and the prototypic member of the serpin super family. The 52-kD Serpin A1a protein is coded by the gene SERPINA1. Serpin A1a plays an important role in modulating immunity, inflammation, proteostasis, apoptosis, and possibly cellular senescence programs. Systemic deficiency in Serpin A1a due to genetic mutations can result in liver failure and chronic lung disease such as emphysema[1]. |
