Recombinant Human Aldehyde Dehydrogenase 1-A3, His 是在 N 端帶有 His 標簽的人重組 ALDH1A3，在大腸桿菌中產(chǎn)生，并表達編碼 Met1-Pro512 的靶基因
Synonyms
rHuAldehyde Dehydrogenase 1-A3, His; ALDH-1A3; Aldehyde Dehydrogenase 1-A3 ; 重組人醛脫氫酶 1-A3，His
Species
HumanSource
E. coli Accession
P47895 Gene ID
220 Molecular Weight
55-60 kDa AA Sequence
HHHHHHMATA NGAVENGQPD RKPPALPRPI RNLEVKFTKI FINNEWHESK SGKKFATCNP STREQICEVE EGDKPDVDKA VEAAQVAFQR GSPWRRLDAL SRGRLLHQLA DLVERDRATL AALETMDTGK PFLHAFFIDL EGCIRTLRYF AGWADKIQGK TIPTDDNVVC FTRHEPIGVC GAITPWNFPL LMLVWKLAPA LCCGNTMVLK PAEQTPLTAL YLGSLIKEAG FPPGVVNIVP GFGPTVGAAI SSHPQINKIA FTGSTEVGKL VKEAASRSNL KRVTLELGGK NPCIVCADAD LDLAVECAHQ GVFFNQGQCC TAASRVFVEE QVYSEFVRRS VEYAKKRPVG DPFDVKTEQG PQIDQKQFDK ILELIESGKK EGAKLECGGS AMEDKGLFIK PTVFSEVTDN MRIAKEEIFG PVQPILKFKS IEEVIKRANS TDYGLTAAVF TKNLDKALKL ASALESGTVW INCYNALYAQ APFGGFKMSG NGRELGEYAL AEYTEVKTVT IKLGDKNP Biological Activity
Data is not available. Appearance
Solution Formulation
Supplied as a 0.2 μm filter solution of 20 mM Tris-HCl, 150 mM NaCl, 20% Glycerol, pH 7.5. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
N/A Storage & Stability
Recombinant Human Aldehyde Dehydrogenase 1-A3, His (rHuAldehyde Dehydrogenase 1-A3, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Shipping with dry ice. Background
Aldehyde Dehydrogenase 1-A3 (ALDH1A3) catalyzes the oxidation of retinal to the pleiotropic factor retinoic acid using NAD+. ALDH1A3 participates in various physiological processes in human cells by oxidizing all-trans-retinal to retinoic acid. ALDH1A3 influences a diverse range of biological characteristics within cancer stem cells and can act as a marker for these cells. ALDH1A3 is differentially activated during early embryonic head and forebrain development. ALDH1A3 is considered a target in breast cancer. High expression of ALDH1A3 has been observed in high-grade gliomas (HGGs)[1][2]. |
