Recombinant Human ADAM-like protein decysin-1, His (HEK293-expressed) 是在 C 端帶有 6His 標(biāo)簽的人重組 ADAMDEC1，通過哺乳動物表達(dá)系統(tǒng)在人細(xì)胞中產(chǎn)生，并表達(dá)編碼 Ile31-Glu470 的靶基因。
Synonyms
rHuADAM-like protein decysin-1, His; ADAMDEC-1; ADAM-like protein decysin-1 ; 重組人 ADAM 樣蛋白 decysin-1，His (HEK293 細(xì)胞表達(dá))
Species
HumanSource
HEK 293 Accession
O15204 Gene ID
27299 Molecular Weight
Approximately 38.0 kDa AA Sequence
KSPEKEDFLR AQKYIDLYLV LDNAFYKNYN ENLTLIRSFV FDVMNLLNVI YNTIDVQVAL VGMEIWSDGD KIKVVPSAST TFDNFLRWHS SNLGKKIHDH AQLLSGISFN NRRVGLAASN SLCSPSSVAV IEAKKKNNVA LVGVMSHELG HVLGMPDVPF NTKCPSGSCV MNQYLSSKFP KDFSTSCRAH FERYLLSQKP KCLLQAPIPT NIMTTPVCGN HLLEVGEDCD CGSPKECTNL CCEALTCKLK PGTDCGGDAP NHTTEHHHHH H Biological Activity
Data is not available. Appearance
Solution Formulation
Supplied as a 0.2 μm filter solution of 20 mM Tris, 150 mM NaCl, 1 mM ZnCl2, pH 7.5. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
N/A Storage & Stability
Recombinant Human ADAM-like protein decysin-1, His (HEK293-expressed) (rHuADAM-like protein decysin-1, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Shipping with dry ice. Background
ADAM-like Decysin-1 (ADAMDEC1) is a member of the ADAM family and a secreted type of metalloprotease. ADAMDEC1 contains a signal peptide, a prodomain, a catalytic domain, and an incomplete disintegrin domain. ADAMDEC1 contains the ADAM consensus sequence for the proteolytic activity and exhibits a metalloproteinase activity for α2-macroglobulin (α2M) in vitro. The expression of ADAMDEC1 is upregulated in the mix culture of normal and RasV12-transformed epithelial cells, which facilitates apical extrusion of the transformed cells[1]. |
