Recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) 是一種 CC 趨化因子，能夠通過 CCR1 誘導(dǎo)內(nèi)皮細(xì)胞的遷移和管系形成。
Synonyms
rHuMPIF/CCL23, 85a.a.; C-C motif chemokine 23; SCYA23; MPIF-1; Ck-beta8; MIP-3 ; 重組人MPIF/CCL23,85a.a (CHO 表達(dá))
Species
HumanSource
CHO Accession
P55773 Gene ID
6368 Molecular Weight
Approximately 11.3 kDa AA Sequence
RFHATSADCC ISYTPRSIPC SLLESYFETN SECSKPGVIF LTKKGRRFCA NPSDKQVQVC VRMLKLDTRI KTRKN Biological Activity
The EC50 is <1 μg/mL as measured on Ca2+ mobilization assay in CHO-K1/Gα15/hCCR1 cells (human Gα15 and human CCR5 stably expressed in CHO-K1 cells). Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) (rHuMPIF/CCL23, 85a.a.) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) (rHuMPIF/CCL23, 85a.a.) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Human CCL23 (also known as CKb8, MPIF-1, or MIP-3) is a CC chemokine, which induces endothelial cell migration and tube formation via CCR1. CCL23 also exhibits chemotactic activity on monocytes and dendritic cells, and inhibits the formation of bone marrow-derived colony-forming cells[1]. |
