Recombinant Human Interleukin-17A, His (CHO-expressed) 是一種細胞因子，在先天免疫和后天免疫中發(fā)揮重要作用。
Synonyms
rHuIL-17A, His; CTLA-8; IL-17A ; 重組人白介素-17A (CHO 細胞表達)
Species
HumanSource
CHO Accession
Q16552 Gene ID
3605 Molecular Weight
14-22 kDa AA Sequence
GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VAHHHHHH Biological Activity
The ED50 is <10 ng/mL as measured by NHDF cells, corresponding to a specific activity of >1 × 105 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Interleukin-17A, His (CHO-expressed) (rHuIL-17A, His) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Interleukin-17A, His (CHO-expressed) (rHuIL-17A, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
IL-17A plays important roles in both innate and acquired immunity and is, especially, involved in the accumulation of polymorphonuclear neutrophil leukocytes. IL-17A mediates crucial crosstalk between the immune system and various epithelial tissues, initiating a series of defensive mechanisms against bacterial and fungal infections[1]. |
