Recombinant Human HVEM, Fc Chimera (Sf9 insect cells-expressed) 是一種皰疹病毒的進入介質(zhì),介導(dǎo)多種野生型兩種血清型 HSV 的進入。 Synonyms rHuHVEM, Fc Chimera; TNFRSF14; TR2; CD270; HVEA ; 重組人 HVEM Fc 嵌合體 (Sf9 昆蟲細胞表達) Species HumanSource Sf9 insect cells Accession Q92956 Gene ID 8764 Molecular Weight Approximately 45 kDa AA Sequence LPSCKEDEYP VGSECCPKCS PGYRVKEACG ELTGTVCEPC PPGTYIAHLN GLSKCLQCQM CDPAMGLRAS RNCSRTENAV CGCSPGHFCI VQDGDHCAAC RAYATSSPGQ RVQKGGTESQ DTLCQNCPPG TFSPNGTLEE CQHQTKRSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGK Biological Activity The ED50 is <0.1 μg/mL as measured by 929 cells, corresponding to a specific activity of >1 × 104 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human HVEM, Fc Chimera (Sf9 insect cells-expressed) (rHuHVEM, Fc Chimera) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human HVEM, Fc Chimera (Sf9 insect cells-expressed) (rHuHVEM, Fc Chimera) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background HVEM mediates the entry of several wild-type HSV strains of both serotypes. HVEM is active inmediating HSV-1 entry into human T lymphoblasts[1]. |