Recombinant Human FGFR-1 alpha, Fc Chimera (Sf9 insect cells-expressed) 是成纖維細(xì)胞生長因子受體的成員之一。
Synonyms
rHuFGFR-1α, Fc Chimera; BFGFR; CD331; FLT-2 ; 重組人 FGFR-1 alpha, Fc 嵌合體 (Sf9 昆蟲細(xì)胞表達(dá))
Species
HumanSource
Sf9 insect cells Accession
P11362; P01857 Gene ID
2260 Molecular Weight
Approximately 90 kDa AA Sequence
RPSPTLPEQA QPWGAPVEVE SFLVHPGDLL QLRCRLRDDV QSINWLRDGV QLAESNRTRI TGEEVEVQDS VPADSGLYAC VTSSPSGSDT TYFSVNVSDA LPSSEDDDDD DDSSSEEKET DNTKPNPVAP YWTSPEKMEK KLHAVPAAKT VKFKCPSSGT PNPTLRWLKN GKEFKPDHRI GGYKVRYATW SIIMDSVVPS DKGNYTCIVE NEYGSINHTY QLDVVERSPH RPILQAGLPA NKTVALGSNV EFMCKVYSDP QPHIQWLKHI EVNGSKIGPD NLPYVQILKT AGVNTTDKEM EVLHLRNVSF EDAGEYTCLA GNSIGLSHHS AWLTVLEALE ERPAVMTSPL YLEGSGSGSG SPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK Biological Activity
The ED50 is <2 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >5 × 105 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human FGFR-1 alpha, Fc Chimera (Sf9 insect cells-expressed) (rHuFGFR-1α, Fc Chimera) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human FGFR-1 alpha, Fc Chimera (Sf9 insect cells-expressed) (rHuFGFR-1α, Fc Chimera) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
FGFR are one of nine subclasses of tyrosine kinase receptors, divided into four distinct types, each encoded by a separate gene: FGFR-1 (flg or fms-like gene), FGFR-2 (bek or bacterial expressed kinase), FGFR-3, and FGFR-4. FGFRs have an extracellular ligand-binding domain and an intracellular domain, which includes the protein tyrosine kinase, separated by the plasma membrane[1]. |
