Recombinant Mouse Fibroblast Growth Factor 8c 是 FGF-8 的亞型，F(xiàn)GF-8 是胚胎發(fā)育過程中的一個(gè)重要因子，參與前列腺癌的進(jìn)展。
Synonyms
rMuFGF-8c; AIGF; HBGF-8 ; 重組人成纖維細(xì)胞生長因子 8c
Species
MouseSource
E. coli Accession
P37237 Gene ID
14179 Molecular Weight
Approximately 28.2 kDa AA Sequence
MQVRSAAQKR GPGAGNPADT LGQGHEDRPF GQRSRAGKNF TNPAPNYPEE GSKEQRDSVL PKVTQRHVRE QSLVTDQLSR RLIRTYQLYS RTSGKHVQVL ANKRINAMAE DGDPFAKLIV ETDTFGSRVR VRGAETGLYI CMNKKGKLIA KSNGKGKDCV FTEIVLENNY TALQNAKYEG WYMAFTRKGR PRKGSKTRQH QREVHFMKRL PRGHHTTEQS LRFEFLNYPP FTRSLRGSQR TWAPEPR Biological Activity
The ED50 is <150 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >6.7 × 103 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse Fibroblast Growth Factor 8c (rMuFGF-8c) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Mouse Fibroblast Growth Factor 8c (rMuFGF-8c) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast Growth Factor 8 is an essential factor during embryonic development, overexpressed in several tumor types. Fibroblast Growth Factor 8 stimulates anti-apoptotic pathways and prevents tumor cell death[1]. |
