Recombinant Human Fibroblast Growth Factor 8a 是 FGF-8 的亞型，F(xiàn)GF-8 是胚胎發(fā)育過程中的一個重要因子，參與前列腺癌的進展。
Synonyms
rHuFGF-8a; AIGF; HBGF-8 ; 重組人成纖維細胞生長因子 8a
Species
HumanSource
E. coli Accession
P55075 Gene ID
2253 Molecular Weight
Approximately 21.3 kDa AA Sequence
MQHVREQSLV TDQLSRRLIR TYQLYSRTSG KHVQVLANKR INAMAEDGDP FAKLIVETDT FGSRVRVRGA ETGLYICMNK KGKLIAKSNG KGKDCVFTEI VLENNYTALQ NAKYEGWYMA FTRKGRPRKG SKTRQHQREV HFMKRLPRGH HTTEQSLRFE FLNYPPFTRS LRGSQRTWAP EPR Biological Activity
The ED50 is <500 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >2 × 103 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 8a (rHuFGF-8a) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human Fibroblast Growth Factor 8a (rHuFGF-8a) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast Growth Factor 8 is an essential factor during embryonic development, overexpressed in several tumor types. Fibroblast Growth Factor 8 stimulates anti-apoptotic pathways and prevents tumor cell death[1]. |
