Recombinant Human Fibroblast Growth Factor 8 是胚胎發(fā)育過程中的一個(gè)重要因子，參與前列腺癌的進(jìn)展。
Synonyms
rHuFGF-8; FGF-8; AIGF; HBGF-8 ; 重組人成纖維細(xì)胞生長因子 8
Species
HumanSource
E. coli Accession
P55075 Gene ID
2253 Molecular Weight
Approximately 22.5 kDa AA Sequence
MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR Biological Activity
The ED50 is <5 ng/mL as measured by TF-1 cells, corresponding to a specific activity of >2 × 105 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 8 (rHuFGF-8) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human Fibroblast Growth Factor 8 (rHuFGF-8) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast Growth Factor 8 is an essential factor during embryonic development, overexpressed in several tumor types. Fibroblast Growth Factor 8 stimulates anti-apoptotic pathways and prevents tumor cell death[1]. |
