Recombinant Human VEGF-D (HEK293-expressed) 是一種促進(jìn)血管再生和淋巴再生的調(diào)節(jié)因子。
Synonyms
rHuVEGF-D; Vascular endothelial growth factor D; FIGF ; 重組人源血管內(nèi)皮生長因子D (HEK293-expressed)
Species
HumanSource
CHO Accession
O43915 Gene ID
2277 Molecular Weight
18-19 kDa AA Sequence
FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR Biological Activity
The ED50 is <1 μg/mL as measured by HUVEC cells. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human VEGF-D (HEK293-expressed) (rHuVEGF-D) to 100 μg/mL using ddH2O or PBS. Storage & Stability
Lyophilized recombinant Human VEGF-D (HEK293-expressed) (rHuVEGF-D) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
VEGF-D, a powerful lymphangiogenic and angiogenic growth factor, is also a major regulator of chylomicron metabolism in mice[1]. Vascular endothelial growth factor D (VEGF-D) has important functions in lymphangiogenesis and angiogenesis. High plasma levels of VEGF-D have been associated with incidence of heart failure. The association of VEGF-D with atrial fibrillation (AF) and stroke is unclear and we hypothesised that VEGF-D could also be associated with incidence of AF and ischaemic stroke[2]. |
