Recombinant Human MIP-5/CCL15 是一種趨化因子，對髓細胞如樹突狀細胞、單核細胞、中性粒細胞和一些 T 淋巴細胞具有很強的趨化性。
Synonyms
rHuMIP-5/CCL15; C-C motif chemokine 15; HCC-2; SCYA15; NCC3 ; 重組人 MIP-5/CCL15
Species
HumanSource
E. coli Accession
Q16663 Gene ID
6359 Molecular Weight
Approximately 10.2 kDa AA Sequence
QFINDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY SI Biological Activity
The ED50 is <2 μg/mL as measured by CHO cells transfected with human CCR1, corresponding to a specific activity of >500 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human MIP-5/CCL15 (rHuMIP-5/CCL15) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human MIP-5/CCL15 (rHuMIP-5/CCL15) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
CCL15 is a chemokine with a strong chemotactic activity for myeloid cells such as dendritic cells, monocytes, neutrophils and some T-lymphocytes[1]. Recombinant Human CCL15 is the most abundant chemokine in follicular thyroid carcinoma (FTC) compared with follicular adenoma (FA)[2]. |
