Recombinant Human MIP-1 beta/CCL4 是一種促趨化因子，既能夠在各種炎癥條件下促進(jìn)白細(xì)胞聚集，又有助于對(duì)人類免疫缺陷 1 型病毒產(chǎn)生免疫保護(hù)
Synonyms
rHuMIP-1β/CCL4; C-C motif chemokine 4; LAG-1; Macrophage inflammatory protein 1-beta; SCYA4 ; 重組人 MIP-1 beta/CCL4
Species
HumanSource
E. coli Accession
P13236 Gene ID
6351 Molecular Weight
Approximately 7.6 kDa AA Sequence
APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN Biological Activity
The ED50 is <100 ng/mL as measured by CHO-K1/Gα15/hCCR5 cells (human Gα15 and human CCR5 stably expressed in CHO-K1 cells). Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human MIP-1 beta/CCL4 (rHuMIP-1β/CCL4) to 100 μg/mL using ddH2O or PBS. Storage & Stability
Lyophilized recombinant Human MIP-1 beta/CCL4 (rHuMIP-1β/CCL4) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Human macrophage inflammatory protein-1 (MIP-1β) 1 is a proinflammatory chemokine that both promotes leukocyte accumulation in various inflammatory conditions and contributes to protective immunity against human immunodeficiency virus type 1 (HIV-1) (1-5)[1]. |
