Recombinant Human MIG/CXCL9 是一種趨化因子，能夠與 CXCR3 結(jié)合，與幾種惡性腫瘤的腫瘤進(jìn)展、免疫逃逸及血管生成有關(guān)。
Synonyms
rHuMIG/CXCL9; C-X-C motif chemokine 9; SCYB9 ; 重組人 MIG/CXCL9
Species
HumanSource
E. coli Accession
Q07325 Gene ID
4283 Molecular Weight
Approximately 11.7 kDa AA Sequence
TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KTT Biological Activity
Full biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10-100 ng/mL. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 50 mM NaCl. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human MIG/CXCL9 (rHuMIG/CXCL9) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Human MIG/CXCL9 (rHuMIG/CXCL9) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Monokine induced by interferon-gamma (MIG/CXCL9) is a chemokine binding to CXCR3, associated with tumor progression, immune escape, and angiogenesis in several malignancies[1]. |
