Recombinant Human GRO beta/CXCL2 是一種功能強(qiáng)大的中性粒細(xì)胞化學(xué)誘導(dǎo)劑，參與多種免疫反應(yīng)，包括傷口愈合、癌癥轉(zhuǎn)移和血管生成。
Synonyms
rHuGRO-β/CXCL2; C-X-C motif chemokine 2; MIP2-alpha; HSF ; 重組人CXC 趨化因子2
Species
HumanSource
E. coli Accession
P19875 Gene ID
2920 Molecular Weight
Approximately 8.0 kDa AA Sequence
APLATELRCQC LQTLQGIHLK NIQSVKVKSP GPHCAQTEVI ATLKNGQKAC LNPASPMVKK IIEKMLKNGK SN Biological Activity
The ED50 is <200 ng/mL as measured by CHO-K1/Gα15/hCXCR2 cells (human Gα15 and human CXCR2 stably expressed in CHO-K1 cells). Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human GRO beta/CXCL2 (rHuGRO-β/CXCL2) to 100 μg/mL using ddH2O or PBS. Storage & Stability
Lyophilized recombinant Human GRO beta/CXCL2 (rHuGRO-β/CXCL2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
CXCL2 is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells[1]. CXCL2, like related chemokines, is also a powerful neutrophil chemoattractant and is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis[2]. |
