Recombinant Bovine Basic Fibroblast Growth Factory 有著廣泛的生物學(xué)功能，包括有絲分裂發(fā)生、細(xì)胞存活、轉(zhuǎn)移形成等。、
Synonyms
rBobFGF; FGF-2; FGF2; FGF 2; HBGF-2 ; 重組牛堿性成纖維細(xì)胞生長(zhǎng)因子
Species
BovineSource
E. coli Accession
P03969 Gene ID
281161 Molecular Weight
Approximately 16.5 kDa AA Sequence
MPALPEDGGS GAFPPGHFKD PKRLYCKNGG FFLRIHPDGR VDGVREKSDP HIKLQLQAEE RGVVSIKGVC ANRYLAMKED GRLLASKCVT DECFFFERLE SNNYNTYRSR KYSSWYVALK RTGQYKLGPK TGPGQKAILF LPMSAKS Biological Activity
The ED50 is <0.1 ng/mL as measured by murine Balb/c 3T3 cells, corresponding to a specific activity of >1.0 × 107 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Bovine Basic Fibroblast Growth Factor (rBobFGF) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Bovine Basic Fibroblast Growth Factor (rBobFGF) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast growth factor 2 (FGF2) is expressed in many cells and tissue types and has been reported to have a wide range of biological effects, including mitogenesis, cell survival, formation of metastases, remodelling and regeneration of tissues, control of cell proliferation and differentiation, regulation of a variety of genes and regulation of gene expression and rRNA transcription. Fibroblast growth factor 2 (FGF2) also plays an important role in fertility and early embryo development[1]. |
