Recombinant Mouse CXCL16 是T細(xì)胞的化學(xué)誘導(dǎo)劑，也是表皮角質(zhì)形成細(xì)胞先天免疫的調(diào)節(jié)劑。
Synonyms
rMuCXCL16; C-X-C motif chemokine 16; SR-PSOX; Srpsox ; 重組小鼠 CXC 趨化因子16 (CXCL16)
Species
MouseSource
E. coli Accession
Q8BSU2 Gene ID
66102 Molecular Weight
Approximately 9.9 kDa AA Sequence
NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLP Biological Activity
Full biological activity determined by a chemotaxis bioassay using murine lymphocytes is in a concentration of 20-1000 ng/ml. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse CXCL16 (rMuCXCL16) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Mouse CXCL16 (rMuCXCL16) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
CXCL16 is shown to be a monocyte chemoattractant[1]. CXCL16 is a membrane-bound chemokine that consists of four distinct domains: the chemokine domain, mucin-like domain, transmembrane domain and ad cytoplasmic CXCL16 is one of the ELR- CXC chemokines, acts as a mediator of innate immunity by attracting CXC chemokine receptor (CXCR) 6-expressing cells, such as activated T cells and NKT cells. CXCL16 is not only a chemokine, but is also a multifunctional protein[2]. |
