Recombinant Mouse Beta Defensin-2 是一種參與對抗微生物入侵反應的抗微生物肽。
Synonyms
rMuBD-2; DEFB2 ; 重組小鼠 β-防御素-2
Species
MouseSource
E. coli Accession
P82020 Gene ID
13215 Molecular Weight
Approximately 5.5 kDa AA Sequence
AVGSLKSIGY EAELDHCHTN GGYCVRAICP PSARRPGSCF PEKNPCCKYM K Biological Activity
Full biological activity determined by a chemotaxis bioassay using immature human dendritic cells is in a concentration of 10-100 ng/ml. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse Beta Defensin-2 (rMuBD-2) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Mouse Beta Defensin-2 (rMuBD-2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Mouse Beta Defensin-2 (mBD2) is produced by mouse urothelium in response to intravesicular BCG as a defense mechanism against BCG, and blocking mBD2 by an anti-mBD2 antibody increased the effectiveness of BCG[1]. |
