Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (CHO-expressed) 是一種細胞因子，能夠促進造血干細胞及其祖細胞的再生和分化。
Synonyms
rHuFlt-3 Ligand; Flt3 ligand; FL; SL cytokine; Flt-3L ; 重組人 Fms 樣酪氨酸激酶 3 配體 (CHO 細胞表達)
Species
HumanSource
CHO Accession
P49771 Gene ID
2323 Molecular Weight
18-22 kDa AA Sequence
TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA Biological Activity
The ED50 is <1 ng/mL as measured by human AML5 cells, corresponding to a specific activity of >1 × 106 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Fms-related Tyrosine Kinase 3 Ligand (CHO-expressed) (rHuFlt-3 Ligand) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Fms-related Tyrosine Kinase 3 Ligand (CHO-expressed) (rHuFlt-3 Ligand) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fms-related tyrosine kinase 3 ligand is a type of cell factor, able to promote the generation and differentiation of hematopoietic stem cells and their progenitor cells. The mRNA of Fms-related tyrosine kinase 3 ligand is highly expressed in certain tissues, including peripheral blood mononuclear cells, the heart, placenta, lung, spleen and thymus tissue, and is also expressed to a certain extent in non-hematopoietic tissues, including the prostate, testis, ovaries, intestines, liver, kidney and skeletal muscle[1]. |
