Recombinant Rat Stem Cell Factor (HEK293-expressed) 是一種造血因子，與它的配體 c-kit 結(jié)合，在造血、精子發(fā)生和黑素生成中起著重要的作用。
Synonyms
rRtSCF; Hematopoietic growth factor KL; MGF; Mast Cell Growth Factor ; 重組大鼠干細(xì)胞因子 (HEK293 細(xì)胞表達(dá))
Species
RatSource
HEK 293 Accession
P21581 Gene ID
60427 Molecular Weight
10-20 kDa AA Sequence
QEICRNPVTD NVKDITKLVA NLPNDYMITL NYVAGMDVLP SHCWLRDMVT HLSVSLTTLL DKFSNISEGL SNYSIIDKLG KIVDDLVACM EENAPKNVKE SLKKPETRNF TPEEFFSIFN RSIDAFKDFM VASDTSDCVL SSTLGPEKDS RVSVTKPFML PPVA Biological Activity
The ED50 is <50 ng/mL as measured by TF-1 cells. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Rat Stem Cell Factor (HEK293-expressed) (rRtSCF) to 100 μg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Rat Stem Cell Factor (HEK293-expressed) (rRtSCF) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Stem Cell Factor is a hematopoietic cytokine, triggered by binding to its ligand c-kit, and plays an important role in hematopoiesis, spermatogenesis, and melanogenesis. Stem Cell Factor (SCF) is applied for hematopoietic stem cell mobilization, exvivo stem/progenitor cell expansion, gene therapy, and immunotherapy[1]. Stem Cell Factor regulates cell survival, proliferation, differentiation, and migration in divergent cell types[2]. |
