| Recombinant Human Bone Morphogenetic Protein 7 是一種有效的骨形成蛋白，同時為轉(zhuǎn)化生長因子 (TGF-β)超家族的一部分，經(jīng)過臨床試驗成功后，可用于修正后外側(cè)腰椎融合及長骨骨折不愈合的癥狀。 MCE 的所有產(chǎn)品僅用作科學研究，我們不為任何個人用途提供產(chǎn)品和服務
Synonyms
rHuBMP-7; OP-1 ; 重組人骨形態(tài)發(fā)生蛋白 7
Species
Human Source
E. coli Accession
P18075 Gene ID
655 Molecular Weight
Approximately 15.7 kDa AA Sequence
STGSKQRSQN RSKTPKNQEA LRMANVAENS SSDQRQACKK HELYVSFRDL GWQDWIIAPE GYAAYYCEGE CAFPLNSYMN ATNHAIVQTL VHFINPETVP KPCCAPTQLN AISVLYFDDS SNVILKKYRN MVVRACGCH Biological Activity
Data is not available. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against solution in 30% acetonitrile, 0.1% TFA. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Bone Morphogenetic Protein 7 (rHuBMP-7) to 0.1-1.0 mg/mL using 10mM HAc. Storage & Stability
Lyophilized recombinant Human Bone Morphogenetic Protein 7 (rHuBMP-7) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Bone morphogenetic protein-7 (BMP-7) is a homodimeric glycoprotein that belongs to the transforming growth factor beta (TGFβ) superfamily, functions in osteogenesis and chondrogenesis, and is involved in various cellular processes such as kidney and eye development, brown adipogenesis, and bone metastasis. Recombinant Human Bone Morphogenetic Protein 7 produced in Chinese hamster ovary (CHO) cells is approved for revision posterolateral lumbar spine fusion and for the treatment of long bone nonunion fractures after successful clinical trials[1]. |
