4007787550
|
 |
||||||||||||||
| 貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
| JD1227179032 | LAT Phospho (pY191) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【產(chǎn)品類型】Rabbit Monoclonal IgG 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】E225 【用途】WB , IHC , ICC , IP 【產(chǎn)品性狀】 【陽(yáng)性對(duì)照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】36/38 kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】LAT (linker f o r activation of T-cells) is involved in the T-cell antigen recept o r (TCR) signal transduction pathway, a n d may play an imp o r tant role downstream in activating protein tyrosine kinases (1). LAT is phosph o r ylated by ZAP-70/Syk protein tyrosine kinases leading to recruitment of multiple signaling molecules (2). It has been found that Tyr191 a n d Tyr171 are required f o r T-cell activation a n d Tyr132 is required f o r the activation of PLCgamma1 a n d Ras signaling pathways, respectively. Tyr226 a n d Tyr191 are required f o r Vav binding, whereas Tyr171 a n d Tyr132 are necessary f o r association a n d activation of phosphoinositide 3-kinase activity a n d PLCgamma1 (3). WB: 1:2,000 A. Western blot analysis on Jurkat cell lysate B. Immunohistochemical analysis of paraffin-embedded |
