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| 貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
| JD1227179014 | JAM1 (N-term) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【產(chǎn)品類型】Rabbit Monoclonal IgG 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EP1042Y 【用途】WB , IHC 【產(chǎn)品性狀】 【陽(yáng)性對(duì)照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】33 kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】Junctional Adhesion Molecules (JAMs) are components a n d regulat o r s of the well- characterized epithelial a n d endothelial tight junction. JAM is s e l e c tively concentrated at intercellular junctions of endothelial a n d epithelial cells of different o r igins. Microscopy shows that JAM codistributes with tight junction components at the apical region of the intercellular cleft. A mAb directed to JAM (BV11) was found to inhibit spontaneous a n d chemokine-induced monocyte transmigration through an endothelial cell monolayer in vitro. Systemic treatment of mice with BV11 mAb blocked monocyte infiltration upon chemokine administration in subcutaneous air pouches (1). The human protein shares a highly conserved structure a n d sequence with the murine protein. However it is distinct in that it is constitutively expressed on circulating neutrophils, monocytes, platelets a n d lymphocyte subsets (2). WB: 1:2000 A. Western blot analysis on HeLa cell lysate using B. Immunohistochemical staining of paraffin-embedded |
