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貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫存 |
JD1227178977 | IFN gamma | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【產(chǎn)品類型】Rabbit Monoclonal Antibody 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EPR1108 【用途】WB , ICC 【產(chǎn)品性狀】 【陽性對(duì)照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】20-25kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】Interferons (IFNs) plays a crucial role in antiviral, antiproliferative, immunomodulatory, antitumor, and antiparasitic activities by inducing transcription of IFN-stimuated genes (ISGs) through activation of the Jak-STAT pathway. In particular, Interferon gamma (IFN γ), a sole member of the Type II IFN family, is involved in lymphocyte activation and the regulation of lymphocyte subsets (proliferation, differentiation) (1). IFN γ is expressed in activated CD4 Th1 cells, CD8 cells, gamma/delta T cells, and activated NK cells. IFN γ expression is induced by IL-2, TNF-α and IL-12 and suppressed by IL-4, IL-10, and TGF-β (2). IFN γ binds to IFN γ receptor (IFNGR), which stimulates various immuno-responses such as macrophages activation and enhancement of the type I IFNs anti-viral and anti-tumor activities. In immunocompetent host cells, IFN γ protects against tumor development and directs immunogenic phenotype (3). IFN γ has been implicated in various human diseases, such as multiple sclerosis and insulin-dependent diabetes mellitus (4). Recommended Applications Products Data Western blot analysis on (A) Molt-4, (B) Jurkat, (C) Western blot analysis on 5 ng of IFN gamma Specificity |
貯存: | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |