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| 貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
| JD1227178976 | ICAM-1 | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【產(chǎn)品類型】Rabbit Monoclonal IgG 【反應特異性】Human 【克隆 ID】EP1442Y 【用途】WB , IHC , ICC 【產(chǎn)品性狀】 【陽性對照】 【產(chǎn)品濃度】 【細胞定位】 【抗原分子量】89 kDa |
| 質量標準： | 【產(chǎn)品介紹】Antigen-specific cell contacts in the immune system are strengthened by antigen- nonspecific interactions, mediated in part by lymphocyte-function associated (LFA) antigens. Recently, ICAM-1 (intercellular adhesion molecule-1) has been defined as a lig a n d f o r LFA-1. Monoclonal antibodies to ICAM-1 block T lymphocyte adhesion to fibroblasts a n d endothelial cells a n d disrupt the interaction between cytotoxic T cells a n d target cells. ICAM-1 is found on leukocytes, fibroblasts, epithelial cells a n d endothelial cells a n d its expression is regulated by inflammat o r y cytokines (1). The n o r mal function of human intercellular adhesion molecule-1 (ICAM-1) is to provide adhesion between endothelial cells a n d leukocytes after injury o r stress. However, ICAM-1 is also used as a recept o r by the maj o r group of human rhinoviruses a n d is a catalyst f o r the subsequent viral uncoating during cell entry (2). Monoclonal antibodies recognize a 95 kDa cell surface glycoprotein the maj o r human rhinovirus recept o r , ICAM-1 (3). WB: 1:2000 A. Western blot analysis on Raji cell lysate B. Immunohistochemical staining of paraffin-embedded |
