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| 貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫(kù)存 |
| JD1227178963 | HOXB4 | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【產(chǎn)品類型】Rabbit Monoclonal Antibody 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EPR1917 【用途】WB , ICC , IP 【產(chǎn)品性狀】 【陽(yáng)性對(duì)照】 【產(chǎn)品濃度】 【細(xì)胞定位】 【抗原分子量】34kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】Homeobox transcription factors (Hox) are highly conserved developmental proteins that are involved in embryonic and early hematopoietic development. Specifically, Homeobox B4 (HoxB4) is a transcription factor that is involved in the developmental regulation of specific positional identities on the anterior-posterior axis of cells. Like all members of the HOX family, HoxB4 is abundantly expressed in primitive hematopoietic stem cells (HSC), but then it declines with lineage-specific terminal differentiation (1). In HSC's, stem cell self-renewal activity is regulated by USF1/2 binding to HoxB4, where binding possibly favors stem cell self-renewal instead of cell differentiation. Jun-B and Fra-1 have been linked to key mediators during cell proliferation and differentiation induced by HoxB4, which leads to an increase in expression of Cyclin D1 and G1 shortening (2). Recommended Applications Products Data Western blot analysis on (A) K562, (B) Jurkat, (C) Immunofluorescent staining of NCCIT cells using Specificity |
| 貯存： | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
