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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227178954 | HLA-DRB1 | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【產(chǎn)品類型】Rabbit Monoclonal Antibody 【反應(yīng)特異性】Human 【克隆 ID】EPR6149 【用途】WB 【產(chǎn)品性狀】 【陽性對照】 【產(chǎn)品濃度】 【細胞定位】 【抗原分子量】30kDa |
質(zhì)量標準: | 【產(chǎn)品介紹】HLA-Drb1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of HLA-Drb1 variations have been described, and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. HLA-Drb1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. HLA-Drb1 is present in all individuals. Variants of HLA-Drb1 are linked with either none or one of the proteins for DRB3, DRB4 and DRB5 (1). Recommended Applications Western blot analysis on human spleen lysate Specificity |
貯存: | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |