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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227178924 | Beta-Actin | -- | 100ul | 3575元 | 現(xiàn)貨 | 3天 |
性狀: | 【產(chǎn)品類型】Rabbit Monoclonal IgG 【反應特異性】Human , Mouse , Rat 【克隆 ID】EP1123Y 【用途】WB , IHC , ICC 【產(chǎn)品性狀】 【陽性對照】 【產(chǎn)品濃度】 【細胞定位】 【抗原分子量】42-43 kDa |
質(zhì)量標準: | 【產(chǎn)品介紹】Beta actin also know as Cytoplasmic Actin is a 43 kDa, highly conserved protein, ubiquitously expressed in all eukaryotic cells. They comprise, along with microtubules, a maj o r component of the cytoskeleton. Actin has been found to be expressed in at least six isomeric f o r ms. It is expressed in heart a n d skeletal striated muscle tissue, a n d in certain smooth muscle tissues, regulating contractile potentials f o r these cells. It is also expressed in the cytoplasm of non-muscle cells, functioning to control cell structure a n d motility (1). Inhibition of glycolysis with 2-deoxyglucose induced a rapid transf o r mation of β-actin-rich pseudopodia a n d prevented cell motility, theref o r e a localized glycolytic supply of energy regulates the f o r mation of β-actin-rich pseudopodial protrusions a n d thereby the motility of invasive tum o r cells (2). β-Actin is a relatively stable cytoskeletal protein n o r mally at a constant level in cells, regardless of experimental treatment o r technical procedure. F o r this reason, measurement of β -Actin is generally used as an internal control f o r experimental err o r . Recommended Applications A. Western blot analysis on 1) T47D and 2) HeLa cell B. Immunohistochemical analysis of paraffin-embedded |
貯存: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |