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貨號 | 品名 | 規(guī)格 | 包裝 | 單價 | 貨期 | 庫存 |
JD1227178922 | Beta Tubulin | -- | 100ul | 3575元 | 現(xiàn)貨 | 3天 |
性狀: | 【產(chǎn)品類型】Rabbit Monoclonal IgG 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EP1331Y 【用途】WB , IHC , ICC , FC , IP 【產(chǎn)品性狀】 【陽性對照】 【產(chǎn)品濃度】 【細胞定位】 【抗原分子量】50 kDa |
質(zhì)量標準: | 【產(chǎn)品介紹】Microtubules are essential parts in eukaryotic cell structures, transp o r tation, a n d mitosis a n d consists mainly of 2 soluble protein subunits, alpha a n d beta tubulin. Beta-tubulin binds to alpha tubulin to f o r m tubulin heterodimer which is post-translationally modified (1). The tubulin dimer complex binds to GTP a n d assembles onto the positive ends of microtubules. After inc o r p o r ation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule inc o r p o r ation (2). Mutation on beta-tubulin has been linked to anti-cancer drug resistance in lung cancers (3). Recommended Applications A. Western blot analysis on HeLa cell lysate using B. Immunohistochemical analysis of paraffin-embedded C. Imunofluorescent staining of HeLa cells using Specificity |
貯存: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |