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| 貨號 | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫存 |
| JD1227177516 | Akt1 Phospho (pT308) | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
| 性狀： | 【反應(yīng)特異性】Human , Mouse 【克隆 ID】EP2107Y 【用途】WB 【抗原分子量】60 kDa |
| 質(zhì)量標(biāo)準(zhǔn)： | 【產(chǎn)品介紹】Akt1/PKBa is a Ser/Thr protein kinase, whose kinase activity plays a key role in various cellular functions, including apoptosis, glycogen synthesis, a n d cell growth. Akt1/PKBa is activated by various growth a n d survival fact o r s (1). Phosph o r ylation on Thr308, Ser473 a n d Tyr474 is required f o r full activity. Akt1/PKBa inhibits apoptosis by phosph o r ylating a n d inactivating several targets, including caspase-9 (2). Akt1/PKBa regulates glycogen synthesis by phosph o r ylating a n d inactivating glycogen synthase kinase-3a a n d b (3, 4). Three mammalian Akt1/PKBa isof o r ms have been identified.
A. Western blot analysis on NIH 3T3 cell lysates |
