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貨號(hào) | 品名 | 規(guī)格 | 包裝 | 單價(jià) | 貨期 | 庫存 |
JD1227177505 | ACO1 | -- | 100ul | 0元 | 現(xiàn)貨 | 3天 |
性狀: | 【反應(yīng)特異性】Human , Mouse , Rat 【克隆 ID】EPR7225 【用途】WB , ICC , IP 【抗原分子量】98kDa |
質(zhì)量標(biāo)準(zhǔn): | 【產(chǎn)品介紹】Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1) or ACO1, is a cytosolic protein that binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. ACO1 was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes (1).
WB, ICC, IP WB: 1:1,000 - 10,000 Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Specificity A synthetic peptide corresponding to residues in human |
貯存: | Storage Condition and Buffer Store at -20° C. Buffer: Antibody buffer, sodium |